Clinical Trials (GI Cancer)

Patients at the Multidisciplinary Gastrointestinal Oncology Center have access to many clinical trials conducted by the University of Alabama Comprehensive Cancer Center.

The following clinical trials may be available to Multidisciplinary Gastrointestinal Oncology Center patients.

This list changes frequently as new studies open and old ones close.

Disease Protocol Description
Anal Cancer RTOG 9811 RT + 5-FU + Mito-C vs. RT + 5-FU + CDDP
Bile Duct Cancer UAB 0001 Phase II Rebeccamycin
Colon/Rectal Cancer UAB 0144 Phase II study of oral Xeloda in combination with intravenous Irinotecan
Colon/Rectal Cancer UAB 0237 Phase II multicenter study of Erbitux™ (Cetuximab) in patients with metastatic colorectal carcinoma
Colon/Rectal Cancer UAB 0135 Phase II study safety and immunogenicity of ALVAC-CEA/B7.1 vaccine
Colon/Rectal Cancer UAB 0249 A feasibility study of Oxaliplatin in combination with an infusional or weekly bolus 5-FU/LV or Capecitabine as first line treatment of patients with advanced colorectal cancer
Colon/Rectal Cancer ECOG N9841 Randomized Phase II equivalence trial of Irinotecan vs. Oxaliplatin in combination with an infusional or weekly bolus 5-FU/LV or Capecitabine as first line treatment of patients with advanced colorectal cancer
Colon/Rectal Cancer UAB 0040 Phase IIB evaluation of Cyclooxygenase-2 activity in surgically resected primary colorectal adenomas and carcinomas after 7 days pretreatment with Celecoxib
Esophageal Cancer UAB 0032 A Phase II study of Irinotecan and Taxotere with concurrent radiotherapy as a preoperative treatment in resectable esophageal cancer
Gallbladder Cancer UAB 0001 Phase II Rebeccamycin
Liver Cancer UAB 0034 A Phase I/II open label study of T138057-sodium in patients with advanced, surgically unresectable hepatocellular carcinoma
Liver Cancer UAB 0001 Phase II Rebeccamycin
Pancreatic Cancer UAB 0105 Phase III PN-401 with High Dose 5FU vs. Gemcitabine
Pancreatic Cancer UAB 0133 Phase I/II open label study of Capecitabine with concurrent radiotherapy
Pancreatic Cancer UAB 0243 Randomized, placebo-controlled, double blind Phase II study of Gemcitabine + Ly293111 compared to Gemcitabine + placebo in patients with locally advanced or metastatic pancreatic cancer
All cancers may be elligible UAB 0142 Phase I DX-8951f in patients with liver dysfunction
All cancers may be elligible UAB 0143 Phase I DX-891f in patients with renal dysfunction
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