Pregnyl, Ovidrel (recombinant hCG)
hCG products include Profasi, Pregnyl, and Ovidrel (recombinant hCG). Profasi and Pregnyl are derived from the human placenta. Ovidrel is derived from genetic recombinant technology using mammalian cells and is 100% identical to human hCG.
These products are used to trigger ovulation in ART patients and in some stimulated IUI cycles. LH, released by the pituitary, normally triggers ovulation but it is “blocked” in patients receiving either Lupron or Antagon. The body reacts to an hCG spike in the same manner as the LH spike, thus triggering ovulation.