Skin Pigment Disorders

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What are skin pigment disorders?

Skin color is determined by a pigment (melanin) made by specialized cells in the skin (melanocytes). The amount and type of melanin determines a person's skin color.

What is the function of melanin?

Melanin gives color to the skin, hair, and iris of the eyes. Levels of melanin depend on race and amount of sunlight exposure. Sun exposure increases melanin production - to protect the skin against harmful ultraviolet rays. In addition, hormonal changes can affect melanin production.

What are the different types of skin pigment disorders?

Pigment Disorder	Characteristics	Treatment
albinism	This rare, inherited disorder is characterized by a total or partial lack of melanin in the skin, compared to the pigmentation of siblings and parents. Albinos (people with albinism) have white hair, pale skin, and pink eyes. Vision is often affected.	There is no cure for albinism. Albinos should avoid sunlight because they lack natural protection from sunlight - melanin.
melasma	Dark brown, symmetric patches of pigment on the face. During pregnancy this is called the "mask of pregnancy."	Sunscreens and avoiding sun exposure can prevent melasma from becoming worse. Other treatment may include prescription creams to lighten the patches.
pigment loss after skin damage	Sometimes, following an ulcer, blister, burn, or infection, the skin does not replace some of the pigment in that area.	No treatment is necessary. Cosmetics can usually cover the blemish.
vitiligo	Smooth, white patches in the skin, vitiligo is caused by the loss of pigment-producing cells in the skin (melanocytes). The white patches are very sensitive to the sun.	There is no cure for vitiligo. Treatment may include covering smaller patches with long-lasting dyes, light-sensitive drugs, in addition to ultraviolet A light therapy, corticosteroid creams, and depigmentation of the remaining skin.