UAB Synopsis, Vol. 24, No. 17, May 9, 2005
Harvey Lodish, PhD, renowned scientist and professor of biology and bioengineering at the Massachusetts Institute of Technology (MIT), is the 14th annual Paulette Shirey Pritchett Endowed Lecturer in Pathology. His lecture, "Hematopoietic Stem Cells: Regulation by Novel Surface Proteins, Growth Factors, and Micro RNAs" will be presented at 4 pm on May 11 in Spain Auditorium.
Dr. Lodish is one of the founding members of the Whitehead Institute for Biomedical Research, a leading nonprofit research and educational institution that has created a legacy of research excellence and academic eminence since 1982.
Dr. Lodish's group has elucidated steps in the folding and oligomerization of proteins within the endoplasmic reticulum and developed probes for redox state measurements within the organelle. His group also is studying how micro RNAs regulate hematopoiesis and fat, muscle cell development, and metabolism; how the erythropoietin receptor prevents apoptosis and controls proliferation and differentiation of erythroid progenitor cells; and new marker cell surface proteins and growth factors for hematopoietic stem cells.
Dr. Lodish has served on numerous editorial boards, including the Proceedings of the National Academy of Sciences, Journal of Cell Biology, and Journal of Biological Chemistry and Nucleic Acids Research. He is lead author of the textbook Molecular Cell Biology. The 5th edition, published in 2003, has been translated into six languages.
He has served on advisory panels for the National Institutes of Health, National Science Foundation, and American Cancer Society, the advisory board of the University of Basle's Biozentrum and European Molecular Biology Laboratory in Heidelberg, and the board of trustees at Kenyon College and Massachusetts Eye and Ear Infirmary. Dr. Lodish is a recipient of the National Institute of Diabetes and Digestive and Kidney Diseases Merit Award and the American Diabetes Association Sadie Award.
Paulette Shirey Pritchett, MD, for whom the lectureship is named, was a valued faculty member of UAB's Department of Pathology from 1975 to 1984.